Diaphragm and body weight in emphysema.

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Diaphragm and body weight in emphysema.

The weight of the diaphragm has been investigated in 103 male patients and 81 female patients, and the relationship between body weight and emphysema has been assessed in 662 male and 431 female patients. Diaphragm weight is related to body weight in both male (r = + 0.76) and female patients (r = +0.77) and is relatively larger in the former. Dissecting the diaphragm free of fat or freeze dryi...

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Volume displaced by diaphragm motion in emphysema.

To examine the effect of hyperinflation on the volume displaced by diaphragm motion (DeltaVdi), we compared nine subjects with emphysema and severe hyperinflation [residual volume (RV)/total lung capacity (TLC) 0.65 +/- 0.08; mean +/- SD] with 10 healthy controls. Posteroanterior and lateral chest X rays at RV, functional residual capacity, one-half inspiratory capacity, and TLC were used to me...

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Diaphragm mechanics in dogs with unilateral emphysema.

We studied dogs with unilateral papain-induced emphysema to answer two questions: (1) Do emphysema lung-apposed hemidiaphragm (DiE) and normal lung-apposed hemidiaphragm (DiN) have equal capacities for lowering lung surface pressure? and (2) Are side-to-side differences in intrathoracic pressure the result of unequal force outputs by DiE and DiN or are they caused by differences in their mechan...

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Ultrastructural Changes in the Diaphragm of Aged Emphysema- tous Hamsters

In emphysematous hamsters the diaphragm is continuously exposed to an increased workload. Previous lightmicroscopical observations showed only minor changes in relatively young emphysematous hamsters. However, ageing affects the regenerating capacity of muscles. We hypothesised that the diaphragm of aged emphysematous hamsters shows an increase of ultrastructural alterations in comparison to ag...

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Effects of emphysema on diaphragm blood flow during exercise.

Chronic hyperinflation of the lung in emphysema displaces the diaphragm caudally, thereby placing it in a mechanically disadvantageous position and contributing to the increased work of breathing. We tested the hypothesis that total and regional diaphragm blood flows are increased in emphysema, presumably reflecting an increased diaphragm energetic demand. Male Syrian Golden hamsters were rando...

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ژورنال

عنوان ژورنال: Thorax

سال: 1978

ISSN: 0040-6376

DOI: 10.1136/thx.33.4.483